|
Symbol Name ID |
Bank1
B cell scaffold protein with ankyrin repeats 1 MGI:2442120 |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukopenia |
Pericarditis |
Lymphadenopathy |
Lupus nephritis |
Nephritis |
Abnormality of the immune system |
Discoid lupus rash |
Malar rash |
Serositis |
Decreased circulating complement C3 concentration |
Decreased circulating complement C4 concentration |
Autoimmunity |
Antineutrophil antibody positivity |
Perinuclear antineutrophil antibody positivity |
Antinuclear antibody positivity |
Anti-dsDNA antibody positivity |
Anti-La/SS-B antibody positivity |
Anti-Sm antibody positivity |
Anti-U1 ribonucleoprotein antibody positivity |
Antiphospholipid antibody positivity |
Systemic lupus erythematosus |
| Disease(s) Associated with BANK1 | |||||||||||||||||||||
| systemic lupus erythematosus | |||||||||||||||||||||
| type 1 diabetes mellitus |
| Mouse Phenotypes | increased B cell proliferation |
increased mature B cell number |
increased B-1a cell number |
abnormal spleen germinal center morphology |
increased spleen germinal center number |
increased spleen germinal center size |
abnormal splenic cell ratio |
abnormal lymphocyte physiology |
abnormal B cell physiology |
increased IgG2a level |
increased IgM level |
|
| Availability | Mouse Genotype | |||||||||||
| Bank1tm1Kuro/Bank1tm1Kuro | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools